
Dr. Dorottya Nagy-Szakal, MD, PhD
Clinical metagenomics • Translational medicine • Urinary tract infections • Joint infections • Microbiome research • NGS diagnostics • Antimicrobial resistance • FDA regulatory strategy
Dr. Dorottya Nagy-Szakal is the Chief Medical Officer of Biotia, where she oversees clinical operations, medical affairs, and regulatory strategy for the company's metagenomic infectious disease diagnostics.
Dr. Dorottya Nagy-Szakal, MD, PhD
Dr. Dorottya Nagy-Szakal is the Chief Medical Officer of Biotia, where she oversees clinical operations, medical affairs, and regulatory strategy for the company's metagenomic infectious disease diagnostics.
Clinical metagenomics • Translational medicine • Urinary tract infections • Joint infections • Microbiome research • NGS diagnostics • Antimicrobial resistance • FDA regulatory strategy
About Dr. Dorottya Nagy-Szakal
Dr. Dorottya Nagy-Szakal is the Chief Medical Officer of Biotia, where she oversees clinical operations, medical affairs, laboratory leadership, and strategic communications with regulatory bodies including the FDA and CDC. She brings more than 15 years of experience in translational medicine and clinical microbiology, with deep expertise in clinical metagenomics for urine, joint fluid, and other challenging infections using next-generation sequencing technologies.
Before joining Biotia, Dr. Nagy-Szakal led clinical research on fecal microbiota transplantation, the gut-brain axis, multi-omics of complex disease, and COVID-19 diagnostics and therapeutics. She has authored more than 30 peer-reviewed articles in high-impact journals including JAMA, Nature Communications, Cell, mBio, and Scientific Reports, as well as multiple book chapters.
Dr. Nagy-Szakal earned her MD and PhD in clinical medicine from Semmelweis University of Medicine in Budapest, Hungary. She completed postdoctoral fellowships at Baylor College of Medicine / Texas Children's Hospital and Columbia University Medical Center. She currently serves as a research assistant professor at SUNY Downstate Health Sciences University.
Education
- MD, Semmelweis University of Medicine, Budapest, Hungary
- PhD in Clinical Medicine, Semmelweis University of Medicine, Budapest, Hungary
- Postdoctoral Fellowship, Baylor College of Medicine / Texas Children's Hospital
- Postdoctoral Fellowship, Columbia University Medical Center
Affiliations
- SUNY Downstate Health Sciences University (Research Assistant Professor)
- Baylor College of Medicine / Texas Children's Hospital (former postdoc)
- Columbia University Medical Center (former postdoc)
Publications and Blogs from Dr. Dorottya Nagy-Szakal
Selected publications
Autologous fecal microbiota transplantation restores the infant gut microbiome and metabolome after antibiotics: a case report.
Analytical validation of a metagenomic next-generation diagnostic platform for urinary tract infection in a Thai tertiary hospital setting: a BI-Biotia UTI cohort study.
Mucosal disease activity may predict response to fecal microbiota transplantation in patients with ulcerative colitis.
Potential Application of a Clinical-Grade Next Generation Sequencing Assay for Detection of Bacterial Vaginosis Associated Organisms in Urine.
Comprehensive Next-Generation Sequencing-Based Assay for Antimicrobial Resistance Gene Marker Identification in Urine.
Comparative Effectiveness of Single vs Repeated Rapid SARS-CoV-2 Antigen Testing Among Asymptomatic Individuals in a Workplace Setting.
Fecal Microbiota Transplantation Commonly Failed in Children With Co-Morbidities.
Targeted Hybridization Capture of SARS-CoV-2 and Metagenomics Enables Genetic Variant Discovery and Nasal Microbiome Insights.
Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics.
Fecal metagenomic profiles in subgroups of patients with myalgic encephalomyelitis/chronic fatigue syndrome.
Utilization of Clinical-Grade Metagenomics in Urinary Tract Infection Diagnostics: Improving High-Risk Patients' Outcomes with a Genomic-Based Assay.
Serial fecal microbiota transplantation alters mucosal gene expression in pediatric ulcerative colitis.
The Gut Microbiome in the Nutrition-Infection Interaction: A Focus on Malnourished Children.
Mucosal expression of claudins in celiac disease.
The remarkable capacity for gut microbial and host interactions.
Blog posts

What Is a UTI? Causes, Symptoms, and Diagnosis
UTI 101
UTI Symptoms: What to Look For and When to See a Doctor
UTI 101
The Tripledemic: Why Viruses Are Hitting Harder This Year and What Can Be Done
Industry News
New Antibiotic Drug Shows Success in Treating UTIs After 20 Years
Industry News
Resistance on the Rise: The Increase of AMR During and Post-Pandemic
Research and Evidence
Svante Pääbo Receives Nobel Prize for DNA Sequencing Technology
Clinical Metagenomics
Sepsis Awareness: The Current Global Health Crisis and What We Can Do About It
Clinical Metagenomics
Exploring Novel Therapeutics for C. difficile Awareness Month
Microbiome Science
Running with Trillions of Microbes: The Microbiome of a Marathoner
Microbiome Science
Hitchhiker Resistance Genes in International Travelers
Research and Evidence
