BIOTIA‑DX: bringing clinical accuracy to pathogen research

BIOTIA-DX is a powerful pathogen genomic analysis platform. Use the same clinical-grade bioinformatics that power our diagnostic assay to identify pathogens, track variants, and detect antimicrobial resistance. BIOTIA-DX offers reliable insights to enhance pathogen research.

Use_on_GeoSeeq
Acquire_license

BIOTIA‑DX

BIOTIA-DX pipelines process sequencing data to identify pathogens, detect genetic variants, and assess antimicrobial resistance. Each pipeline provides detailed outputs like assembled genomes, lineage identification, and resistance gene detection. Users receive comprehensive reports with actionable insights for pathogen research.

Urine
Influenza

BIOTIA-DX Urine

Clinical Grade Metagenomics

BIOTIA-DX Urine is a clinical-grade bioinformatic tool designed to analyze urinary tract infections with exceptional accuracy. It uses next-generation sequencing and advanced algorithms to identify a wide range of pathogens and antimicrobial resistance genes.

‍

With 97% sensitivity and 99% specificity, it delivers precise and comprehensive results. BIOTIA-DX Urine is optimized for clinical use, providing reliable insights to support the diagnosis and management of both routine and complex urinary tract infection cases.

‍

Key Features

  • Species identification with clinical-grade accuracy
  • Identify antimicrobial resistance genes and mutations
  • Comprehensive data report with visualizations
  • Works with NGS and ONT

‍

This software is for research use only unless used as part of the BIOTIA-ID Urine Clinical Assay
View a Sample Project

BIOTIA-DX Influenza

Analyze Influenza - Beta Release

BIOTIA-DX Influenza is a cutting-edge bioinformatic tool designed to analyze avian influenza virus genomes using next-generation sequencing data. It performs H and N typing, subtypes highly pathogenic avian influenza variants, and identifies key genetic traits linked to virulence and transmissibility.

‍

This tool helps researchers efficiently process and interpret AIV genomic data, enabling them to track emerging variants and understand their epidemiological impact. BIOTIA-DX Influenza delivers actionable insights to support surveillance and public health responses to avian influenza outbreaks.

‍

Key Features

  • Determine segment types, clades, and H5 subclades
  • Identify cleavage sites and mutations
  • Comprehensive data report with visualizations
  • Works with NGS, ONT, and Sanger sequencing

‍

For research use only
View a Sample Project
About Our Work

An Overview of Avian Influenza Surveillance and Genomics

Biotia's head of bioinformatics, Dr. Wells, presents on the genomics of avian influenza. Learn what mutations create conditions for an outbreak and how genomics can be used for biosurveillance and prevention.

Watch_full_presentation

Offering clinical-grade metagenomic tools for researchers

97%

sensitivity

99%

specificity

We have optimized BIOTIA-DX in clinical assays for varied specimen types. Paired with our optimized lab workflows we have attained lower limits of detection than culture with high sensitivity and specificity.

Why choose
BIOTIA‑DX

Existing metagenomic tools require coding or bioinformatic expertise and often return a long list of microbial species. We have optimized BIOTIA-DX to be easy to use and have a low rate of false-positive hits so researchers can focus on their research questions.

AI-based metagenomic software to detect viruses, bacteria, fungi, protozoa, and AMR

Drill down to individual SNPs for strain-level identification

97% sensitivity,
99% specificity in clinical studies

Identify species from a comprehensive database of 7000+ clinically-curated microbes

Works with single-end, paired-end, and long-read data

Innovating through partnership with industry leaders

Built with NASA

We have worked with NASA JPL developing components of our analysis pipeline and analyzing samples from the international space station to identify and describe novel bacterial and fungal strains, and published this work widely.

View_publications

MAYO Clinic

Biotia joined the Mayo Clinic Platform to strengthen the clinical components of BIOTIA-DX and validate our approach on clinical data.

There is great promise in using metagenomics for infectious disease diagnostics, especially for challenging or drug resistant infections.

View_publications

Featured publications

View_all
Coming soon

The Challenges and Opportunities in Creating an Early Warning System for Global Pandemics (pre-print)

Environmental Testing Using NGS
Read_poster
Read_article
Coming soon

Ozone Disinfection for Elimination of Bacteria and Degradation of SARS-CoV2 RNA for Medical Environments

COVID-19 Work
Read_poster
Read_article
Coming soon

Comparative Effectiveness of Single vs Repeated Rapid SARS-CoV-2 Antigen Testing Among Asymptomatic Individuals in a Workplace Setting

COVID-19 Work
Read_poster
Read_article

How to access BIOTIA‑DX

BIOTIA‑DX is available as an app on the GeoSeeq platform. Please contact us for a license.

Use_on_GeoSeeq
Acquire_license

Read documentation and FAQs

View_documentation