Biotia
For Health Systems

What is BIOTIA-DX?

BIOTIA-DX is our pathogen genomic analysis platform that allows researchers and healthcare facilities to identify pathogens, track variants, and detect antimicrobial resistance. License our software or engage with us for isolate and outbreak detection services.

What it is

A pathogen genomic analysis platform with broad applicability

Biotia's proprietary bioinformatic pipelines, called BIOTIA-DX, process next-generation sequencing data to identify pathogens, detect genetic variants, and profile antimicrobial resistance.

Genome assembly

Lineage identification

Resistance gene detection

Why BIOTIA-DX

Pathogen genomics made easy

Existing metagenomic tools require coding or bioinformatic expertise and often return a long list of microbial species. We have optimized BIOTIA-DX to be easy to use and have a low rate of false-positive hits so researchers can focus on their research questions and healthcare facilities can stay on top of infection prevention and antimicrobial stewardship efforts.

AI-based metagenomic software to detect viruses, bacteria, fungi, protozoa, and AMR

Drill down to individual SNPs for strain-level identification

Identify species from a comprehensive database of 7,000+ clinically-curated microbes

Works with single-end, paired-end, and long-read data

View case studies
HOSPITAL SERVICES

BIOTIA-DX Isolate & Outbreak

BIOTIA-DX Isolate & Outbreak is a highly-customizable service provided to healthcare facilities. Through this service, Biotia is able to provide facilities with rapid genomic analysis of bacterial and fungal isolates to support infection control and antimicrobial stewardship.

BIOTIA-DX Isolate

BIOTIA-DX Isolate brings best in class genomic analysis to pathogen isolate sequencing. Remove any ambiguity about your isolated cultures with deep taxonomic characterization and genomic resistance analysis. Identify precise strain types for different species and, with BIOTIA-DX Outbreak, find outbreak clusters.

Key features
  • Determine species and strain from a database of thousands of organisms
  • Predict antimicrobial resistance with BIOTIA-DX RESISTANCE
  • Tag samples with LPSN taxonomy
  • Assemble and annotate genome for downstream analysis
  • Determine strain through custom cgMLST
  • Characterize plasmids such as those that carry mecA
  • Disambiguate tricky species groups like E. coli, Shigella, and Klebsiella
  • Works with BIOTIA-DX Outbreak for outbreak cluster analysis
  • Validated on Illumina and ONT data

BIOTIA-DX Outbreak

BIOTIA-DX Outbreak provides critical information to infection control teams. Find clusters of closely related pathogens and identify sources of transmission. Track changing drug resistance patterns over time. Compare your facility's samples to publicly available outbreak genomes to identify community-acquired vs facility-acquired outbreaks.

Key features
  • Identify clonal complexes of microbial isolates
  • Phylogenetic trees to visualize organism relatedness
  • Custom cgMLSTs determine relatedness based on thousands of genomic markers
  • Grow analysis as more samples are collected
  • Find and track transmission patterns
  • Compare to community acquired microbes
View case studies
Research & development

Innovating in partnership with industry leaders

BIOTIA-DX is used by leading institutions across the globe. Learn more about our partners below.

NASA logo

NASA

We have worked with NASA JPL developing components of our analysis pipeline and analyzing samples from the International Space Station to identify and describe novel bacterial and fungal strains, and have published this work widely.

Mayo Clinic logo

Mayo Clinic

Biotia joined the Mayo Clinic Platform to strengthen the clinical components of BIOTIA-DX and validate our approach on clinical data. There is great promise in using metagenomics for infectious disease diagnostics, especially for challenging or drug-resistant infections.

Contact

Get in touch

To license our software or use our isolate and outbreak detection services, contact us at info@biotia.io.