Biotia
For Providers

What is the BIOTIA‑ID Joint Fluid Test?

The BIOTIA-ID Joint Fluid Test is a clinical metagenomic-based diagnostic test for patients with joint infections.

At a glance

Next-generation joint infection testing

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Comprehensive joint infection pathogen detection

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Outperforms standard culture

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Optimized antimicrobial therapy with drug resistance profiling

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Available as research-use only (RUO)

What it is

Advanced diagnostic testing for joint infections

Clinical metagenomics is an advanced form of next-generation sequencing (NGS) that looks for pathogen DNA in biological samples, providing a more complete picture of the microbial community present. The BIOTIA-ID Joint Fluid Test applies this technology to synovial fluid samples to enable comprehensive and highly accurate diagnosis of challenging joint infection cases.

DNA-based detection

Clinical metagenomics allows us to sequence whole pathogen genomes directly from synovial fluid samples, identifying anaerobic bacteria, fungi, and polymicrobial infections.

Drug resistance profiling

Sequencing whole pathogen genomes allows us to detect a broad panel of antibiotic resistance genes to guide targeted therapy and improve antibiotic stewardship efforts.

Research-use only

The BIOTIA-ID Joint Fluid Test is currently available for research-use only. Contact Biotia if you are interested in using this test.

Research & development

Biotia has partnered with Hospital for Special Surgery to develop the BIOTIA-ID Joint Fluid Test

Joint replacement surgery helps millions of people regain mobility and relieve pain every year. Like any surgery, however, there are risks—including prosthetic joint infection, which continues to be a challenge due to its diagnostic complexity. To develop the BIOTIA-ID Joint Fluid Test, Biotia has partnered with Hospital for Special Surgery, the world's leading academic medical center focused on musculoskeletal health.

SEP 2025Business Wire
Biotia and Hospital for Special Surgery Announce Collaboration to Advance Diagnostics for Prosthetic Joint Infections
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